Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25392 | 0.81 | SCD (0.47) | LMNAALDH1A1 | |
| SCHEMBL9830646 | 0.81 | GAA (0.75) | GAALMNAKCNK3KCNK9F2R | |
| SCHEMBL5837400 | 0.80 | TSHR (0.49) | GAALMNAKCNK3KCNK9F2R | |
| SCHEMBL28191716 | 0.79 | RXFP1 (0.50) | GAALMNAKCNK3KCNK9F2R | |
| SCHEMBL6449862 | 0.78 | GAA (0.62) | GAALMNAKCNK3KCNK9KDM4E | |
| SCHEMBL29775613 | 0.78 | LMNA (0.46) | GAALMNAKCNK3KCNK9F2R | |
| SCHEMBL1738337 | 0.78 | LMNA (0.46) | GAALMNAKCNK3KCNK9F2R | |
| SCHEMBL1994129 | 0.76 | TSHR (0.67) | GAALMNAKCNK3KCNK9KDM4E | |
| SCHEMBL16399046 | 0.76 | NPSR1 (0.53) | GAAKDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20827130 | 0.76 | GPR35 (0.60) | GAAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022199-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015008872-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-01-22 | — | — | WO | disclosed |