SCHEMBL16401178

SCHEMBL16401178

Cc1cccc(C)c1NC(=O)NS/N=C/c1ccc2c(ccc3c2nc(C)n3-c2ccc(OC(F)(F)F)cc2)c1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CHRNA7 P36544 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
HPD P32754 1/20 0.32
CRHR1 P34998 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401089 0.89 TTK (0.33) CHRNA7
SCHEMBL19304575 0.88 L3MBTL1 (0.34) L3MBTL1CHRNA7
SCHEMBL16400170 0.85 MAPK1 (0.34)
SCHEMBL16400180 0.84 CHRNA7 (0.40) CHRNA7
SCHEMBL16401043 0.84 TTK (0.31) CHRNA7
SCHEMBL16400863 0.84 CHRNA7 (0.39) L3MBTL1CHRNA7
SCHEMBL16400898 0.84 GCGR (0.34)
SCHEMBL16400845 0.83 L3MBTL1 (0.34) L3MBTL1TRPV1
SCHEMBL19315736 0.83 MEN1 (0.37) POLBL3MBTL1HPDCRHR1
SCHEMBL16401182 0.83 LMNA (0.45) POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP claimed
US-9497970-B2 Pesticide compounds BASF SE (DE) 2016-11-22 US claimed
US-20160157491-A1 Pesticide Compounds BASF SE (DE) 2016-06-09 US claimed
EP-3022185-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2016-05-25 EP claimed
WO-2015007682-A1 PESTICIDE COMPOUNDS BASF SE (DE) 2015-01-22 WO claimed
EP-3022185-B1 PESTICIDE COMPOUNDS BASF SE (DE) 2017-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160157491-A1 Pesticide Compounds C1R, C1S, CBR3 POLB 4660/4885L3MBTL1 705/4885CHRNA7 261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.