Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.55 |
| ▸ | ARG2 | P78540 | 3/20 | 0.55 |
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19305277 | 1.00 | ARG1 (0.55) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL18954910 | 1.00 | ARG1 (0.55) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL16401653 | 1.00 | ARG1 (0.55) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL1975910 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL1975908 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL19357334 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL18954850 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL22862319 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL19305278 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT | |
| SCHEMBL18954854 | 0.98 | ARG1 (0.53) | ARG1ARG2GGT1ACLYMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280431-B1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | UNIV GEORGIA (US) | 2023-11-08 | — | — | EP | disclosed |
| US-11773146-B2 | Disruption of the WAVE3 protein complex for suppression of invasion and metastasis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230220019-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINERICH REPEAT KINASE 2 (LRRK2) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2023-07-13 | — | — | US | disclosed |
| US-11299518-B2 | Fusion respiratory syncytial virus inhibitors and use thereof | FONDATION THE ARK (CH) | 2022-04-12 | — | — | US | disclosed |
| US-20210024595-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2021-01-28 | — | — | US | disclosed |
| US-10822380-B2 | Disruption of the WAVE3 protein complex for suppression of invasion and metastasis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2020-11-03 | — | — | US | disclosed |
| US-20180362587-A1 | Compositions and Methods for Inhibiting CBP80 Binding to PGC1 Family of Co-Activators | UNIVERSITY OF ROCHESTER | 2018-12-20 | — | — | US | disclosed |
| US-20180072782-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2018-03-15 | — | — | US | disclosed |
| EP-3280431-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | University of Georgia Research Foundation Inc. (US) | 2018-02-14 | — | — | EP | disclosed |
| WO-2017099821-A1 | COMPOSITIONS AND METHODS FOR INHIBITING CBP80 BINDING TO PGCI FAMILY OF CO-ACTIVATORS | UNIVERSITY OF ROCHESTER (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2016164768-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-10-13 | — | — | WO | disclosed |
| WO-2015010048-A1 | CHEMICALLY-STABILIZED A KINASE ANCHORING PROTEIN (AKAP) PEPTIDE DISRUPTORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220019-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINERICH REPEAT KINASE 2 (LRRK2) | LRRK2, TLK2, LMTK2 | ARG1 4424/4885ARG2 3024/4885GGT1 1852/4885 |
| US-20180362587-A1 | Compositions and Methods for Inhibiting CBP80 Binding to PGC1 Family of Co-Activators | CREB1, NCOA1, CREBBP | ARG1 378/4885ARG2 680/4885GGT1 1360/4885 |
| US-11299518-B2 | Fusion respiratory syncytial virus inhibitors and use thereof | BST2, TMPRSS4, TMPRSS2 | ARG1 1590/4885ARG2 1157/4885GGT1 1241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.