Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401892 | 0.92 | POLB (0.49) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16401549 | 0.86 | EPHX1 (0.54) | RAB9AALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL16401693 | 0.77 | EPHX1 (0.60) | KMT2ARAB9AMEN1ALDH1A1TSHR | |
| SCHEMBL16401475 | 0.75 | CYP1A2 (0.47) | POLBKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL16401739 | 0.75 | EPHX1 (0.48) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL16401885 | 0.73 | POLB (0.50) | POLBKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL16401909 | 0.72 | EPHX1 (0.45) | KMT2ARAB9AMEN1MAPTALDH1A1 | |
| SCHEMBL16401566 | 0.69 | EPHX1 (0.44) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL16401779 | 0.69 | EPHX1 (0.54) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL16401891 | 0.69 | CA9 (0.50) | POLBKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |