Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | LHCGR | P22888 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401693 | 0.91 | EPHX1 (0.60) | EPHX1RAB9AALDH1A1FAAHLHCGR | |
| SCHEMBL16401477 | 0.86 | POLB (0.49) | SMN1; SMN2RAB9AALDH1A1FAAH | |
| SCHEMBL16401739 | 0.84 | EPHX1 (0.48) | EPHX1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL16401909 | 0.83 | EPHX1 (0.45) | EPHX1SMN1; SMN2RAB9AALDH1A1FAAH | |
| SCHEMBL16401892 | 0.77 | POLB (0.49) | EPHX1SMN1; SMN2RAB9AALDH1A1FAAH | |
| SCHEMBL16401779 | 0.77 | EPHX1 (0.54) | EPHX1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7181896 | 0.76 | EPHX1 (0.60) | EPHX1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL16401700 | 0.76 | EPHX1 (0.55) | EPHX1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL16401617 | 0.75 | FAAH (0.46) | EPHX1SMN1; SMN2RAB9AALDH1A1FAAH | |
| SCHEMBL16401900 | 0.75 | EPHX1 (0.51) | EPHX1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | claimed |
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |