Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LHCGR | P22888 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401549 | 0.91 | EPHX1 (0.54) | EPHX1ALDH1A1RAB9AFAAHLHCGR | |
| SCHEMBL16401892 | 0.86 | POLB (0.49) | EPHX1ALDH1A1RAB9AFAAHMEN1 | |
| SCHEMBL16401909 | 0.83 | EPHX1 (0.45) | EPHX1ALDH1A1RAB9AFAAHMEN1 | |
| SCHEMBL16401700 | 0.82 | EPHX1 (0.55) | EPHX1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL16401779 | 0.81 | EPHX1 (0.54) | EPHX1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL16401900 | 0.81 | EPHX1 (0.51) | EPHX1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL16401477 | 0.77 | POLB (0.49) | ALDH1A1RAB9AFAAHMEN1KMT2A | |
| SCHEMBL16401635 | 0.77 | EPHX1 (0.49) | EPHX1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL12196005 | 0.75 | EPHX1 (1.00) | EPHX1ALDH1A1RAB9AFAAHMEN1 | |
| SCHEMBL16401828 | 0.75 | EPHX1 (0.50) | EPHX1ALDH1A1RAB9AFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | claimed |
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |