SCHEMBL16401565

SCHEMBL16401565

Cc1cccc(Cn2cc(COC(=O)NC3CCCCC3)nn2)c1

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TYR P14679 1/20 0.45
KDM1A O60341 1/20 0.45
EPHX1 P07099 1/20 0.44
ACKR3 P25106 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16401890 0.88 ACHE (0.50) HPGDSMN1; SMN2KDM1AEPHX1
SCHEMBL16401697 0.88 EPHX1 (0.55) EPHX1
SCHEMBL16401827 0.85 HDAC1 (0.53) EPHX1ACKR3
SCHEMBL16401633 0.82 HDAC1 (0.52) HPGDEPHX1
SCHEMBL21733296 0.81 EPHX1 (0.61) SMN1; SMN2EPHX1
SCHEMBL16401555 0.80 ACHE (0.43) EPHX1
SCHEMBL16401885 0.80 POLB (0.50) SMN1; SMN2ACKR3
SCHEMBL16401778 0.80 EPHX1 (0.53) HPGDSMN1; SMN2EPHX1
SCHEMBL16401738 0.78 SMN1; SMN2 (0.51) SMN1; SMN2EPHX1
SCHEMBL16401891 0.77 CA9 (0.50) HPGDSMN1; SMN2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015007613-A1 O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) 2015-01-22 WO disclosed