Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401778 | 0.89 | EPHX1 (0.53) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16401738 | 0.89 | SMN1; SMN2 (0.51) | EPHX1ALDH1A1CYP19A1ACHEHDAC1 | |
| SCHEMBL16401890 | 0.89 | ACHE (0.50) | EPHX1CYP19A1ACHEHDAC1MEN1 | |
| SCHEMBL16401827 | 0.88 | HDAC1 (0.53) | EPHX1HSP90AB1ACHEHDAC1 | |
| SCHEMBL16401565 | 0.88 | HPGD (0.51) | EPHX1 | |
| SCHEMBL16401555 | 0.85 | ACHE (0.43) | EPHX1ALDH1A1ACHEGAA | |
| SCHEMBL16401633 | 0.85 | HDAC1 (0.52) | EPHX1HDAC1MEN1KMT2A | |
| SCHEMBL16401690 | 0.83 | MEN1 (0.59) | EPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL16401601 | 0.82 | EPHX1 (0.44) | EPHX1ALDH1A1 | |
| SCHEMBL16401817 | 0.80 | EPHX1 (0.43) | EPHX1ALDH1A1ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |