Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17351757 | 0.69 | IDO1 (0.46) | HTR2AHTR2C | |
| SCHEMBL16401309 | 0.69 | TYR (0.58) | HSP90AB1ROCK2 | |
| SCHEMBL16401906 | 0.68 | HDAC1 (0.49) | HSP90AB1KCNH2ROCK2 | |
| SCHEMBL172225 | 0.67 | HTR2A (0.46) | HTR2AHTR2C | |
| SCHEMBL8926 | 0.67 | TAAR1 (0.52) | HTR2AHTR2C | |
| SCHEMBL29792655 | 0.67 | TAAR1 (0.52) | HTR2AHTR2C | |
| SCHEMBL16401596 | 0.67 | SIGMAR1 (0.51) | PSEN1PSEN2KCNH2APH1BNCSTN | |
| SCHEMBL21346105 | 0.66 | HTR2A (0.52) | KCNH2HTR2AHTR2CROCK2 | |
| SCHEMBL16401630 | 0.66 | HDAC1 (0.51) | CD74MIFHSP90AB1 | |
| SCHEMBL3533385 | 0.66 | HTR2A (0.44) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |