Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401822 | 0.83 | NOTUM (0.36) | SIGMAR1MGAMGAASIMGAM2 | |
| SCHEMBL15924647 | 0.82 | NOTUM (0.57) | SIGMAR1MGAMGAASIMGAM2 | |
| SCHEMBL17283071 | 0.82 | MGAM (0.54) | SIGMAR1MGAMGAASIMGAM2 | |
| SCHEMBL17961123 | 0.81 | L3MBTL1 (0.61) | SIGMAR1MGAMGAASIMGAM2 | |
| SCHEMBL16401421 | 0.81 | TYR (0.59) | SIGMAR1ROCK2GSK3BAURKBCYP11B1 | |
| SCHEMBL16401868 | 0.81 | CD74 (0.48) | SMN1; SMN2NPC1RAB9AGBA1 | |
| SCHEMBL16401703 | 0.81 | GPR55 (0.55) | GAAL3MBTL1ALDH1A1PSEN1PSEN2 | |
| SCHEMBL16401906 | 0.80 | HDAC1 (0.49) | SIGMAR1MGAMGAASIMGAM2 | |
| SCHEMBL16401451 | 0.80 | CYP19A1 (0.61) | NPC1RAB9A | |
| SCHEMBL17961125 | 0.78 | SIGMAR1 (0.48) | SIGMAR1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |