Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134588 | 0.74 | TSHR (0.54) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL1004028 | 0.68 | TSHR (0.58) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL5283405 | 0.67 | KDM4E (0.50) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL4735612 | 0.66 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| Hydrochloric Acid SCHEMBL15690391 | 0.66 | TSHR (0.56) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL5723905 | 0.66 | HSPA5 (0.61) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL10604923 | 0.66 | MAPT (0.46) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL1161694 | 0.66 | CDC7 (0.50) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL6510427 | 0.66 | MAPT (0.38) | ALDH1A1KDM4ETSHRMAPTHPGD | |
| SCHEMBL27940354 | 0.66 | CYP1A2 (0.45) | ALDH1A1KDM4ETSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |