Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731252 | 0.77 | AHR (0.38) | MAP4K4EGFR | |
| SCHEMBL2960189 | 0.73 | TGFBR1 (0.33) | EGFRTSHRLMNAMAPTKDR | |
| SCHEMBL30967550 | 0.73 | JAK2 (0.50) | JAK2JAK3SMN1; SMN2TDP1 | |
| SCHEMBL22110128 | 0.73 | MAP4K4 (0.33) | MAP4K4EGFRTSHRTDP1 | |
| SCHEMBL29846190 | 0.67 | PDPK1 (0.41) | CYP1A2PDPK1KDR | |
| SCHEMBL30967648 | 0.67 | MCHR1 (0.44) | TSHRJAK2MEN1LMNACYP1A2 | |
| Formic Acid SCHEMBL30454470 | 0.67 | HDAC6 (0.31) | LMNA | |
| SCHEMBL2959947 | 0.67 | MAP4K4 (0.39) | MAP4K4EGFRALOX15JAK2JAK3 | |
| SCHEMBL2849283 | 0.65 | MAP4K4 (0.46) | MAP4K4MAPTSMN1; SMN2TDP1 | |
| SCHEMBL2640482 | 0.65 | JAK2 (0.54) | MAP4K4JAK2JAK3PTK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3021827-A1 | DYE COMPOSITION COMPRISING A PARTICULAR AMPHOTERIC SURFACTANT AND A SULFATE OR SULFONATE SURFACTANT | L'OREAL (FR) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015007917-A1 | DYE COMPOSITION COMPRISING A PARTICULAR AMPHOTERIC SURFACTANT AND A SULFATE OR SULFONATE SURFACTANT | L'OREAL (FR) | 2015-01-22 | — | — | WO | disclosed |