Formic Acid

Formic Acid

SCHEMBL30454470

CN(C)c1cc2c(O)cccn2n1.O=CO

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30455129 0.71 JAK2 (0.39) KDM4EALDH1A1LMNAGLAGAA
Formic Acid SCHEMBL30455236 0.69 EGFR (0.35) KDM4E
Formic Acid SCHEMBL30455255 0.68 HRH3 (0.37) HDAC6KDM4EALDH1A1LMNAGLA
SCHEMBL16401692 0.67 MAP4K4 (0.35) LMNA
SCHEMBL2960189 0.67 TGFBR1 (0.33) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL3207646 0.64 MAP4K4 (0.46)
Formic Acid SCHEMBL27512036 0.60 TRPA1 (0.43) KDM4EALDH1A1LMNAGAA
SCHEMBL13403443 0.60 KDM4E (0.64) KDM4EALDH1A1LMNAGLAGAA
SCHEMBL2959947 0.58 MAP4K4 (0.39) KDM4EALDH1A1LMNAGAA
Formic Acid SCHEMBL27994873 0.58 CYP2D6 (0.47) KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143708-A Polysubstituted benzazepine heteroaryl derivative and application thereof 四川汇宇制药股份有限公司 2023-05-23 CN disclosed