Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828784 | 0.89 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL31556051 | 0.89 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL12714672 | 0.89 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL2281663 | 0.89 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL3821714 | 0.89 | TYMP (0.59) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL9017501 | 0.89 | TYMP (0.58) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL9238078 | 0.89 | TYMP (0.58) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL32677371 | 0.89 | TYMP (0.58) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL31342955 | 0.88 | TYMP (0.61) | TYMPKDM4EPOLA1TAS1R3TAS1R1 | |
| SCHEMBL16401430 | 0.87 | TYMP (0.53) | TYMPKDM4EPOLA1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004131-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM Chemicals Llc (US) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014197714-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM CHEMICALS LLC (US) | 2014-12-11 | — | — | WO | disclosed |