Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 6/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401943 | 0.86 | TYMP (0.49) | TYMP | |
| SCHEMBL29812366 | 0.85 | ADORA1 (0.44) | TYMPADORA1NT5E | |
| SCHEMBL16401939 | 0.84 | TYMP (0.42) | TYMP | |
| SCHEMBL28226983 | 0.79 | TYMP (0.48) | TYMPADORA1NT5ENSD3TRDMT1 | |
| SCHEMBL7563202 | 0.77 | ADORA1 (0.38) | TYMPADORA1NT5E | |
| SCHEMBL4464738 | 0.76 | TYMP (0.45) | TYMPADORA1NT5ETRDMT1CARM1 | |
| SCHEMBL7061902 | 0.76 | ADORA2A (0.43) | TYMPADORA1NSD3CARM1DOT1L | |
| SCHEMBL7897645 | 0.76 | TYMP (0.50) | TYMP | |
| SCHEMBL1774838 | 0.74 | TYMP (0.63) | TYMPADORA1NT5E | |
| SCHEMBL7871248 | 0.74 | TYMP (0.63) | TYMPADORA1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004131-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM Chemicals Llc (US) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014197714-A1 | PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES | AM CHEMICALS LLC (US) | 2014-12-11 | — | — | WO | disclosed |