SCHEMBL7061902

SCHEMBL7061902

COc1ccc(C(c2ccccc2)(c2ccc(OC)cc2)[C@]2(n3cnc4c(N)ncnc43)C[C@H](O)[C@@H](CO)O2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.43
ADORA3 P0DMS8 2/20 0.43
SLC28A1 O00337 2/20 0.43
ADORA1 P30542 3/20 0.41
PI4KA P42356 3/20 0.40
PI4K2B Q8TCG2 3/20 0.40
PI4K2A Q9BTU6 3/20 0.40
PI4KB Q9UBF8 3/20 0.40
NSD3 Q9BZ95 1/20 0.39
SLC28A2 O43868 2/20 0.39
GMPS P49915 1/20 0.37
CARM1 Q86X55 1/20 0.37
ADORA2B P29275 2/20 0.37
TYMP P19971 1/20 0.37
DPP4 P27487 1/20 0.37
MEN1 O00255 1/20 0.37
MAP3K7 O43318 1/20 0.37
GAPDH P04406 1/20 0.37
MAPK1 P28482 1/20 0.37
STAT6 P42226 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28249867 0.92 ADORA3 (0.49) ADORA2AADORA3SLC28A1ADORA1PI4KA
SCHEMBL1068569 0.83 ADORA1 (0.44) ADORA2AADORA3SLC28A1ADORA1PI4KA
SCHEMBL735544 0.82 ADORA3 (0.39) ADORA2AADORA3ADORA1ADORA2BMAPK1
SCHEMBL10430365 0.80 ADORA2A (0.42) ADORA2AADORA3SLC28A1ADORA1PI4KA
SCHEMBL11040441 0.78 ADORA1 (0.40) ADORA2AADORA3ADORA1ADORA2BMAPK1
SCHEMBL10481812 0.77 ADORA1 (0.37) ADORA2AADORA3ADORA1ADORA2B
SCHEMBL5859569 0.76 PI4KA (0.43) ADORA2AADORA3SLC28A1ADORA1PI4KA
SCHEMBL10381790 0.76 ADORA1 (0.43) ADORA2AADORA3SLC28A1ADORA1PI4KA
SCHEMBL16401780 0.76 TYMP (0.45) ADORA1NSD3CARM1TYMPDOT1L
SCHEMBL3813881 0.76 ADORA1 (0.46) ADORA2AADORA3SLC28A1ADORA1PI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431453-A Phosphorus (V) based reagent, method for the production thereof, and use thereof for producing stereoregular organic phosphorus (V) compounds 百时美施贵宝公司 2025-02-14 CN disclosed
EP-4090664-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS Bristol-Myers Squibb Company (US) 2022-11-23 EP disclosed
WO-2021146391-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C–P BONDS BRISTOL-MYERS SQUIBB COMPANY (US) 2021-07-22 WO disclosed
EP-3004131-A1 PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES AM Chemicals Llc (US) 2016-04-13 EP disclosed
WO-2014197714-A1 PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES AM CHEMICALS LLC (US) 2014-12-11 WO disclosed
WO-2003042658-A2 METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS ACLARA BIOSCIENCES, INC. (US) 2003-05-22 WO disclosed