Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | TYMP | P19971 | 8/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | NADK | O95544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563202 | 0.88 | ADORA1 (0.38) | ADORA1TYMPNT5EEGFRSLC28A1 | |
| SCHEMBL29720399 | 0.86 | ADORA1 (0.40) | ADORA1NT5EEGFRSLC28A1P2RX3 | |
| SCHEMBL2952014 | 0.86 | SLC28A1 (0.48) | ADORA1EGFRSLC28A1ADORA3ADORA2A | |
| SCHEMBL16401780 | 0.85 | TYMP (0.45) | ADORA1TYMPNT5E | |
| Phosphoric Acid SCHEMBL20702110 | 0.83 | SLC28A1 (0.46) | ADORA1EGFRSLC28A1P2RX3P2RX4 | |
| SCHEMBL28226983 | 0.79 | TYMP (0.48) | ADORA1TYMPNT5EEGFR | |
| SCHEMBL8576963 | 0.79 | ADORA2A (0.41) | ADORA1EGFRSLC28A1ADORA3ADORA2A | |
| SCHEMBL29817041 | 0.78 | SLC28A1 (0.45) | ADORA1EGFRSLC28A1ADORA3ADORA2A | |
| SCHEMBL4464738 | 0.76 | TYMP (0.45) | ADORA1TYMPNT5EEGFR | |
| SCHEMBL7066994 | 0.76 | ADORA1 (0.48) | ADORA1TYMPNT5ESLC28A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989235-A | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2022-09-02 | — | — | CN | disclosed |