Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401700 | 0.89 | EPHX1 (0.55) | EPHX1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL16401566 | 0.88 | EPHX1 (0.44) | EPHX1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL16401828 | 0.84 | EPHX1 (0.50) | EPHX1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL16401635 | 0.84 | EPHX1 (0.49) | EPHX1RAB9AHPGDNAAANPC1 | |
| SCHEMBL16401739 | 0.80 | EPHX1 (0.48) | EPHX1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL16401779 | 0.80 | EPHX1 (0.54) | EPHX1RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL16401693 | 0.74 | EPHX1 (0.60) | EPHX1RAB9AMEN1KMT2A | |
| SCHEMBL16401892 | 0.72 | POLB (0.49) | EPHX1RAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL16401900 | 0.72 | EPHX1 (0.51) | EPHX1RAB9AHPGDCYP2C19MEN1 | |
| SCHEMBL16401890 | 0.71 | ACHE (0.50) | EPHX1RAB9ASMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |