Olmesartan Medoxomil

Olmesartan Medoxomil

SCHEMBL16403

CCCc1nc(C(C)(C)O)c(C(=O)OCc2oc(=O)oc2C)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1

The experimentally established mechanism targets of Olmesartan Medoxomil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AGTR1 known ✓ P30556 13/20 1.00
AGTR2 P50052 12/20 1.00
ABCC3 O15438 1/20 1.00
ABCC4 O15439 1/20 1.00
ABCB11 O95342 1/20 1.00
CYP3A4 P08684 1/20 1.00
PDE4D Q08499 1/20 1.00
PDE3A Q14432 1/20 1.00
SLCO1B3 Q9NPD5 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
SLCO1B1 Q9Y6L6 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Olmesartan Medoxomil SCHEMBL28341316 1.00 AGTR1 (1.00) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL29087653 1.00 AGTR1 (1.00) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL27822335 0.99 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL27934840 0.99 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL4132257 0.99 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28547990 0.99 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28754180 0.99 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28754188 0.99 AGTR1 (0.97) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28754174 0.99 AGTR1 (0.97) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL29067178 0.97 AGTR1 (0.95) AGTR1AGTR2ABCC3ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20551 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747238-A1 PROCESS FOR PREPARING INTERMEDIATES OF SARTAN ACTIVE COMPOUNDS Sanofi (FR) 2026-05-27 EP claimed
CN-121015662-B Olmesartan medoxomil amlodipine hydrochlorothiazide three-compound preparation and preparation method and application thereof 上海腾瑞制药股份有限公司 2026-05-12 CN claimed
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-3934654-B1 ISTAROXIME OR ITS METABOLITE PST-3093 FOR USE AS INTRAVENOUS FORMULATION FOR THE TREATMENT OF ACUTE HEART FAILURE (AHF) WINDTREE THERAPEUTICS INC (US) 2026-04-29 EP claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260083726-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR TREATING CANCER USING TUMOR TREATING FIELDS, CHEMOTHERAPEUTIC AGENTS, AND ANTI-FIBROTIC AGENTS NOVOCURE GMBH (CH) 2026-03-26 US claimed
EP-4215194-B1 COMBINATION THERAPY OF AT1 R BLOCKER AND CCR2 INHIBITOR FOR THE TREATMENT, AMELIORATION OR PREVENTION OF A KIDNEY DISEASE DIMERIX BIOSCIENCE PTY LTD (AU) 2026-03-25 EP claimed
US-12582601-B2 Orodispersible powder composition BIOPHARMA SYNERGIES, S.L. (ES) 2026-03-24 US claimed
EP-4709364-A1 THERAPEUTIC FORMULATIONS FOR KIDNEY DISEASE COMPRISING REPAGERMANIUM OR PROPAGERMANIUM AND/OR AT1R BLOCKERS Dimerix Bioscience Pty Ltd (AU) 2026-03-18 EP claimed
EP-1258258-A1 Implantable device comprising a stent and angiotensin II receptor antagonists TERUMO KABUSHIKI KAISHA (JP) 2002-11-20 EP claimed
US-20020168393-A1 Implantable medical material and implantable medical device TERUMO KABUSHIKI KAISHA (JP) 2002-11-14 US claimed
WO-2002079778-A2 IN VIVO DELIVERY METHODS AND COMPOSITIONS RHEOLOGICS, INC. (US) 2002-10-10 WO claimed
WO-2002043806-A2 IN VIVO DELIVERY METHODS AND COMPOSITIONS RHEOLOGICS, INC (US) 2002-06-06 WO claimed
US-20020061835-A1 Administering a drug to a human which is pharmaceutically effective to regulate at least one of the blood parameters used to adjust distribution of the drug through the bloodstream RHEOLOGICS, INC. 2002-05-23 US claimed
EP-1197226-A1 PREVENTIVES FOR THE RECURRENCE OF CEREBROVASCULAR FAILURE AND AGENTS FOR AMELIORATING TROUBLES FOLLOWING CEREBROVASCULAR FAILURE AND INHIBITING PROGRESS THEREOF Takeda Chemical Industries, Ltd. (JP) 2002-04-17 EP claimed
US-20020032149-A1 Monitoring blood flow parameter of bloodstream, administering substance to organism such that an amount of substance enters bloodstream; distributing portion of amount ofsubstance target within organism RHEOLOGICS, INC. 2002-03-14 US claimed
WO-2002015933-A2 COMBINATION COMPRISING AN AT1-RECEPTOR ANTAGONIST AND AN INSULIN SECRETION ENHANCER OR AN INSULIN SENSITISER NOVARTIS AG (CH) 2002-02-28 WO claimed
WO-2002015891-A2 PHARMACEUTICAL COMBINATION OF ANGIOTENSIN II ANTAGONISTS AND ACE INHIBITORS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-02-28 WO claimed
US-20010044584-A1 In vivo delivery methods and compositions RHEOLOGICS, INC. 2001-11-22 US claimed