Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Olmesartan Medoxomil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 known ✓ | P30556 | 13/20 | 0.97 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.97 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.97 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.97 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.97 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.97 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.97 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.97 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Olmesartan Medoxomil SCHEMBL28754188 | 1.00 | AGTR1 (0.97) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL27934840 | 0.99 | AGTR1 (0.99) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL28754180 | 0.99 | AGTR1 (0.99) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL28341316 | 0.99 | AGTR1 (1.00) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL29087653 | 0.99 | AGTR1 (1.00) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL16403 | 0.99 | AGTR1 (1.00) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL4132257 | 0.98 | AGTR1 (0.99) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL28547990 | 0.98 | AGTR1 (0.99) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL27822335 | 0.98 | AGTR1 (0.99) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Olmesartan Medoxomil SCHEMBL29067178 | 0.96 | AGTR1 (0.95) | AGTR1AGTR2ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114624203-A | Quality detection method for sodium magnesium olmesate chewable tablets | 正大制药（青岛）有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-114624203-A | Quality detection method for sodium magnesium olmesate chewable tablets | 正大制药（青岛）有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114624203-A | Quality detection method for sodium magnesium olmesate chewable tablets | 正大制药（青岛）有限公司 | 2022-06-14 | — | — | CN | disclosed |