Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.70 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922325 | 0.94 | NOTUM (0.67) | NOTUMCHRNA7CYP2D6ALDH1A1PLK1 | |
| SCHEMBL3025893 | 0.89 | CHRNA7 (0.83) | CHRNA7CYP2D6 | |
| SCHEMBL4638659 | 0.85 | NOTUM (0.70) | NOTUMCHRNA7ALDH1A1PLK1 | |
| SCHEMBL19798360 | 0.84 | CHRNA7 (0.70) | NOTUMCHRNA7CYP2D6ALDH1A1PLK1 | |
| SCHEMBL4465707 | 0.83 | NOTUM (0.63) | NOTUMCHRNA7ALDH1A1 | |
| SCHEMBL2449412 | 0.83 | PLK1 (0.73) | NOTUMCHRNA7ALDH1A1PLK1 | |
| SCHEMBL1980763 | 0.83 | NOTUM (1.00) | NOTUMALDH1A1 | |
| SCHEMBL16403251 | 0.82 | CHRNA7 (0.81) | CHRNA7CYP2D6ALDH1A1 | |
| SCHEMBL5922384 | 0.82 | MAPT (0.68) | NOTUMCHRNA7CYP2D6ALDH1A1PLK1 | |
| SCHEMBL3019756 | 0.81 | CHRNA7 (0.54) | NOTUMCHRNA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657037-B2 | Pyrrole compounds with silicon incorporation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | disclosed |
| US-9657037-B2 | Pyrrole compounds with silicon incorporation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | disclosed |
| US-9657037-B2 | Pyrrole compounds with silicon incorporation | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-23 | — | — | US | disclosed |
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-04-28 | — | — | US | disclosed |
| WO-2014195970-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115181-A1 | NOVEL PYRROLE COMPOUNDS WITH SILICON INCORPORATION | PYCR1, MIF, PGLS | NOTUM 2530/4885CHRNA7 4874/4885CYP2D6 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.