Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404158 | 0.88 | NPC1 (0.50) | ALDH1A1MAPTHSD17B10HPGDNPC1 | |
| SCHEMBL14315442 | 0.86 | NPC1 (0.53) | ALDH1A1MAPTHSD17B10GAAHPGD | |
| SCHEMBL16404114 | 0.85 | NPC1 (0.52) | ALDH1A1MAPTLMNAHPGDNPC1 | |
| SCHEMBL16403962 | 0.85 | NPC1 (0.49) | ALDH1A1MAPTHSD17B10LMNAGAA | |
| SCHEMBL14325740 | 0.83 | MAPT (0.53) | ALDH1A1MAPTHSD17B10LMNAHPGD | |
| SCHEMBL16404120 | 0.82 | NPC1 (0.63) | ALDH1A1MAPTHSD17B10LMNAHPGD | |
| SCHEMBL14325852 | 0.81 | NPC1 (0.66) | ALDH1A1MAPTHSD17B10LMNAHPGD | |
| SCHEMBL16403952 | 0.81 | NPC1 (0.57) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL16403950 | 0.79 | RAB9A (0.52) | ALDH1A1MAPTHSD17B10LMNAHPGD | |
| SCHEMBL14315443 | 0.79 | RAB9A (0.63) | ALDH1A1MAPTHSD17B10LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |