SCHEMBL16404152

SCHEMBL16404152

Cc1nc(-c2c[nH]c(C(=O)N3CCC(O)CC3)c2)cs1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 2/20 0.54
ATP4B P51164 2/20 0.54
ALDH1A1 P00352 5/20 0.50
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 2/20 0.47
CYP46A1 Q9Y6A2 1/20 0.44
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
EIF4E P06730 1/20 0.41
CASP3 P42574 1/20 0.40
CASP2 P42575 1/20 0.40
ABL1 P00519 1/20 0.40
RHOA P61586 1/20 0.40
GAA P10253 4/20 0.40
POLB P06746 2/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16404065 0.89 ATP4A (0.64) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL14318291 0.89 ATP4A (0.67) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL14306191 0.89 ATP4A (0.51) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL14318276 0.88 ATP4A (0.69) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL16404112 0.88 ATP4A (0.53) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL13175467 0.85 AKR1C3 (0.51) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL14318279 0.82 NPC1 (0.57) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL16404143 0.82 ATP4A (0.53) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL14318349 0.81 LMNA (0.51) ATP4AATP4BALDH1A1RAB9ANPC1
SCHEMBL14318274 0.81 HPGD (0.51) ATP4AATP4BALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8937065-B2 Compositions and methods for modulating a kinase CLEVEXEL PHARMA (FR) 2015-01-20 US disclosed