Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403926 | 0.95 | RAB9A (0.38) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16403985 | 0.86 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16404075 | 0.85 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16404058 | 0.83 | SMN1; SMN2 (0.42) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL14224977 | 0.83 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16403919 | 0.83 | JAK2 (0.41) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16403913 | 0.82 | KDM4E (0.42) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16403932 | 0.82 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL14684766 | 0.81 | RAB9A (0.40) | RAB9ANPC1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL16404147 | 0.80 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |