Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.54 |
| ▸ | ATP4B | P51164 | 2/20 | 0.54 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TACR3 | P29371 | 2/20 | 0.47 |
| ▸ | EIF4E | P06730 | 3/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404134 | 0.92 | ATP4A (0.52) | ATP4AATP4BCDC25ACDC25BCDC25C | |
| SCHEMBL14224948 | 0.87 | ATP4A (0.57) | ATP4AATP4BNPC1RAB9AALDH1A1 | |
| SCHEMBL14224939 | 0.84 | ATP4A (0.61) | ATP4AATP4BCDC25ACDC25BCDC25C | |
| SCHEMBL14224940 | 0.84 | ATP4A (0.56) | ATP4AATP4BCDC25ACDC25BCDC25C | |
| SCHEMBL14306167 | 0.84 | ATP4A (0.54) | ATP4AATP4BNPC1RAB9AALDH1A1 | |
| SCHEMBL14224937 | 0.83 | ATP4A (0.53) | ATP4AATP4BNPC1RAB9AALDH1A1 | |
| SCHEMBL14318272 | 0.83 | RAB9A (0.52) | ATP4AATP4BNPC1RAB9AALDH1A1 | |
| SCHEMBL14224914 | 0.82 | HPGD (0.50) | ATP4AATP4BNPC1RAB9AALDH1A1 | |
| SCHEMBL14306165 | 0.81 | ATP4A (0.49) | ATP4AATP4BNPC1RAB9AALDH1A1 | |
| SCHEMBL14224967 | 0.81 | ATP4A (0.57) | ATP4AATP4BNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |