Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404245 | 0.84 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL16404215 | 0.82 | CNR2 (0.41) | CNR2CNR1RIPK1 | |
| SCHEMBL16404231 | 0.68 | CNR2 (0.65) | CNR2CNR1ALDH1A1 | |
| SCHEMBL12720363 | 0.67 | CNR2 (0.56) | CNR2CNR1ALDH1A1 | |
| SCHEMBL16404233 | 0.67 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL16404192 | 0.67 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL16404434 | 0.66 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL16142598 | 0.65 | HTT (0.51) | CNR2ALDH1A1 | |
| SCHEMBL16404420 | 0.64 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL14173484 | 0.64 | CNR2 (0.53) | CNR2CNR1RIPK1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |