Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404192 | 0.78 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL3456908 | 0.76 | MEN1 (0.67) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6084391 | 0.71 | SMN1; SMN2 (0.55) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6083816 | 0.71 | SMN1; SMN2 (0.55) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL29494626 | 0.70 | MEN1 (0.60) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL16404231 | 0.70 | CNR2 (0.65) | CNR2HTTNPSR1CNR1 | |
| SCHEMBL3909801 | 0.70 | EPHX2 (0.63) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9754167 | 0.70 | EPHX2 (0.63) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL1694528 | 0.70 | EPHX2 (0.63) | MEN1HTTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL12053848 | 0.70 | CNR1 (0.60) | CNR2MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |