Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 13/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404209 | 0.82 | CNR2 (0.55) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL16404233 | 0.78 | CNR2 (0.55) | CNR2CNR1 | |
| SCHEMBL16404247 | 0.77 | CNR2 (0.57) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL5315168 | 0.76 | TAS1R3 (0.65) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL5793451 | 0.76 | TAS1R3 (0.65) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL13871306 | 0.75 | CNR2 (0.56) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL14284444 | 0.73 | CNR2 (0.51) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL16404219 | 0.72 | CNR2 (0.42) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL14003103 | 0.71 | CNR2 (0.49) | CNR2TAS1R3TAS1R1CNR1 | |
| SCHEMBL15234328 | 0.71 | TAS1R3 (0.46) | CNR2TAS1R3TAS1R1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |