Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | CNR2 | P34972 | 7/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404248 | 0.92 | CNR1 (0.60) | GRM5CNR1CNR2ALDH1A1 | |
| SCHEMBL31385131 | 0.75 | MAOA (0.61) | NPC1MAOAGAAKDM4EALDH1A1 | |
| SCHEMBL28800170 | 0.74 | PTGER4 (0.52) | NPC1ALDH1A1 | |
| SCHEMBL28800173 | 0.74 | PTGER4 (0.52) | NPC1ALDH1A1 | |
| SCHEMBL2033217 | 0.73 | CNR1 (0.65) | GRM5CNR1CNR2ALDH1A1 | |
| SCHEMBL5644953 | 0.72 | NPC1 (0.88) | NPC1GAAKDM4EALDH1A1 | |
| SCHEMBL16404261 | 0.72 | CNR1 (0.60) | GRM5CNR1CNR2 | |
| SCHEMBL3684239 | 0.72 | CNR1 (0.57) | GRM5CNR1CNR2ALDH1A1 | |
| SCHEMBL16404211 | 0.71 | CNR1 (0.68) | GRM5CNR1CNR2 | |
| SCHEMBL23889217 | 0.71 | CNR1 (0.56) | GRM5NPC1CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |
| US-8937184-B2 | 1H-imidazole derivatives as cannabinoid CB2 receptor modulators | ABBVIE B.V. (NL) | 2015-01-20 | — | — | US | disclosed |