Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029925 | 0.91 | NPC1 (0.82) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL5033348 | 0.86 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL3661213 | 0.85 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL4946074 | 0.85 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL1470784 | 0.85 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL308111 | 0.84 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL3690383 | 0.84 | POLB (0.79) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL12432031 | 0.83 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL5225162 | 0.83 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2ATP53 | |
| SCHEMBL19509670 | 0.82 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2AKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8936840-B2 | Retardation film, polarizing plate, liquid crystal display device, and compound | Konica Minolta, Inc. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-8936840-B2 | Retardation film, polarizing plate, liquid crystal display device, and compound | Konica Minolta, Inc. (JP) | 2015-01-20 | — | — | US | disclosed |