Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.82 |
| ▸ | TP53 | P04637 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | RAB9A | P51151 | 3/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TOP1 | P11387 | 2/20 | 0.63 |
| ▸ | TERT | O14746 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 1/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661213 | 0.94 | NPC1 (0.74) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL1470784 | 0.94 | NPC1 (0.73) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL4946074 | 0.94 | NPC1 (0.73) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL308111 | 0.92 | NPC1 (0.72) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL16404286 | 0.91 | NPC1 (0.70) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL30608697 | 0.91 | NPC1 (0.70) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL651227 | 0.91 | NPC1 (0.70) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL11523681 | 0.91 | NPC1 (1.00) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL16335223 | 0.91 | MEN1 (0.79) | NPC1TP53MEN1KMT2ARAB9A | |
| SCHEMBL12431980 | 0.89 | NPC1 (0.68) | NPC1TP53MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109376-B2 | Benzene and naphthylene derivatives and their use as UV screening agents | DSM IP ASSETS B.V. (NL) | 2006-09-19 | — | — | US | disclosed |
| US-20060153784-A1 | Novel 2-benzoxazolyl benzene derivatives and their use as UV screening agents | HUBER ULRICH | 2006-07-13 | — | — | US | disclosed |
| US-7019020-B2 | 2-benzoxazolyl benzene derivatives and their use as UV screening agents | DSM IP ASSETS B.V. (NL) | 2006-03-28 | — | — | US | disclosed |
| US-20040071640-A1 | Novel-2-benzoxazolyl benzene derivatives and their use as uv screening agents | DSM IP ASSETS B.V. (NL) | 2004-04-15 | — | — | US | disclosed |
| EP-1358167-A1 | NOVEL 2-BENZOXAZOLYL BENZENE DERIVATIVES AND THEIR USE AS UV SCREENING AGENTS | Roche Vitamins AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002062771-A1 | NOVEL 2-BENZOXAZOLYL BENZENE DERIVATIVES AND THEIR USE AS UV SCREENING AGENTS | ROCHE VITAMINS AG (CH) | 2002-08-15 | — | — | WO | disclosed |
| WO-1994025501-A1 | EPOXY RESINS CONTAINING THIADIAZOLE AND/OR OXADIAZOLE MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040071640-A1 | Novel-2-benzoxazolyl benzene derivatives and their use as uv screening agents | CBX8, XRCC5, CYP8B1 | NPC1 2743/4885TP53 1265/4885MEN1 4826/4885 |
| US-20060153784-A1 | Novel 2-benzoxazolyl benzene derivatives and their use as UV screening agents | POLR1C, CBR3, CBR1 | NPC1 2800/4885TP53 521/4885MEN1 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.