Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | VDR | P11473 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.71 |
| ▸ | AHR | P35869 | 1/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.68 |
| ▸ | SYK | P43405 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529342 | 0.90 | MAPT (0.81) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL1083965 | 0.90 | MAPT (0.81) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL7671789 | 0.87 | GAA (0.76) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL8148905 | 0.84 | CYP1A2 (0.72) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL1083765 | 0.84 | MAPT (1.00) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL16404287 | 0.84 | CYP1A2 (0.68) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL29496983 | 0.83 | MAPT (0.68) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL3738391 | 0.83 | MAPT (0.68) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL8140659 | 0.83 | CYP1A2 (0.69) | MAPTCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL29592179 | 0.83 | CYP1A1 (0.97) | CYP1A2KDM4ECYP1A1CYP1B1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | MAPT 4124/4885CYP1A2 18/4885KDM4E 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.