SCHEMBL16404308

SCHEMBL16404308

CC(=O)Oc1ccc(-c2nc(Nc3ccccc3CO)c3ccccc3n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.52
ABCG2 Q9UNQ0 7/20 0.52
KDM4E B2RXH2 5/20 0.52
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
RECQL P46063 1/20 0.51
TP53 P04637 3/20 0.49
POLB P06746 1/20 0.49
PDE5A O76074 2/20 0.49
ABCC1 P33527 1/20 0.49
MAPK1 P28482 2/20 0.48
ADORA3 P0DMS8 1/20 0.48
USP2 O75604 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16404471 0.86 MAPT (0.73) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL2234788 0.76 ABCG2 (0.62) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL2296451 0.76 MEN1 (0.54) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL16404332 0.73 ABCG2 (0.69) MAPTABCG2MEN1KMT2ATP53
SCHEMBL16404481 0.72 ABCG2 (0.80) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL16404355 0.71 ABCG2 (0.78) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL9638586 0.70 ELANE (0.51) MAPTALDH1A1LMNATDP1TP53
SCHEMBL1063734 0.69 MEN1 (0.76) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL4891835 0.69 ABCG2 (0.69) MAPTABCG2KDM4EMEN1KMT2A
SCHEMBL16404494 0.69 ABCG2 (0.95) MAPTABCG2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8936840-B2 Retardation film, polarizing plate, liquid crystal display device, and compound Konica Minolta, Inc. (JP) 2015-01-20 US disclosed