Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895763 | 0.85 | ESR1 (0.46) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL17254798 | 0.79 | ALOX5 (0.48) | ELANENPC1RAB9AHSD17B10MAPT | |
| SCHEMBL8016290 | 0.79 | LMNA (0.57) | ELANENPC1RAB9AHSD17B10MAPT | |
| SCHEMBL29488288 | 0.79 | MAPT (0.58) | NPC1RAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL3343178 | 0.79 | MAPT (0.58) | NPC1RAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL304562 | 0.78 | KDM4E (0.61) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL15689510 | 0.77 | TNKS (0.71) | NPC1RAB9AHSD17B10MAPTALDH1A1 | |
| SCHEMBL1901110 | 0.77 | KDM4E (0.71) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL17254817 | 0.77 | ALOX5 (0.49) | ELANENPC1RAB9AHSD17B10MAPT | |
| SCHEMBL914374 | 0.77 | ALDH1A1 (0.76) | ELANENPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243784-B1 | PHOTOPOLIMERIZABLE COMPOSITION AND PHOTOPOLYMERIZABLE IMAGING MATERIAL CONTAINING IT | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-29 | — | — | EP | disclosed |
| US-5057398-A | Improved photosensitivity | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |