Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.57 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.39 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15318075 | 0.75 | DHODH (0.35) | DHODHGAAKDM4ECHUKMEN1 | |
| SCHEMBL4361606 | 0.73 | — | — | |
| SCHEMBL600613 | 0.70 | — | — | |
| SCHEMBL163701 | 0.70 | — | — | |
| SCHEMBL18120677 | 0.68 | DHODH (1.00) | DHODHGAAGFERKDM4EALDH1A1 | |
| SCHEMBL24610541 | 0.67 | DHODH (0.41) | DHODHGRM5GAAKDM4EMAPK1 | |
| SCHEMBL24610542 | 0.67 | DHODH (0.47) | DHODHJAK2JAK1TYK2JAK3 | |
| SCHEMBL13682951 | 0.65 | DHODH (0.44) | DHODHJAK2JAK1TYK2JAK3 | |
| SCHEMBL13163178 | 0.65 | DHODH (0.49) | DHODHGAAKDM4EKMT2APOLB | |
| SCHEMBL27164099 | 0.65 | SLC5A1 (0.38) | DHODHTYK2JAK3CHUKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8936840-B2 | Retardation film, polarizing plate, liquid crystal display device, and compound | Konica Minolta, Inc. (JP) | 2015-01-20 | — | — | US | disclosed |