SCHEMBL16405409

SCHEMBL16405409

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6c7ccccc7c7ccccc7c6c5)cc4)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
TSPO P30536 1/20 0.41
HDAC4 P56524 1/20 0.41
KMT2A Q03164 2/20 0.39
IL1R1 P14778 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
RAC2 P15153 1/20 0.37
RAC3 P60763 1/20 0.37
CDC42 P60953 1/20 0.37
RAC1 P63000 1/20 0.37
PTGER4 P35408 1/20 0.37
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
MAPK1 P28482 1/20 0.36
DNM1 Q05193 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16405412 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL23156562 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL24900311 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL23156583 1.00 L3MBTL1 (0.55) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL16405426 0.98 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21578626 0.98 L3MBTL1 (0.56) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15479765 0.98 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL16405406 0.98 L3MBTL1 (0.56) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21883301 0.98 L3MBTL1 (0.52) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL23156581 0.97 L3MBTL1 (0.51) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825240-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US disclosed
US-9825240-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-21 US disclosed
US-9660202-B2 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-23 US disclosed
US-9660202-B2 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-23 US disclosed
US-20150364697-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 US disclosed
US-20150364697-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-17 US disclosed
US-20150188057-A1 ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-02 US disclosed
US-20150188057-A1 ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2015-07-02 US disclosed
US-20150021574-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-22 US disclosed
US-20150021574-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-22 US disclosed
US-20150021576-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-22 US disclosed
US-20150021576-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150021576-A1 MATERIAL FOR AN ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME L1CAM, OR10J3, PIEZO1 L3MBTL1 1395/4885KDM4E 3349/4885ATM 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.