Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17935299 | 0.85 | MAPT (0.56) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL25734405 | 0.84 | HCAR3 (0.66) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL23286799 | 0.84 | HCAR3 (0.66) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL23490850 | 0.84 | HCAR3 (0.66) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL2793954 | 0.83 | SMN1; SMN2 (0.51) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL21590188 | 0.82 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL17935301 | 0.82 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL18551284 | 0.81 | MAPT (0.56) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL24900038 | 0.81 | HCAR3 (0.64) | MAPTALDH1A1KMT2AMEN1ALOX12 | |
| SCHEMBL19857884 | 0.81 | MAPT (0.61) | MAPTALDH1A1KMT2AMEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328131-B2 | Benzimidazolium compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-05-03 | — | — | US | disclosed |
| WO-2015007519-A1 | NOVEL BENZIMIDAZOLIUM COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-22 | — | — | WO | disclosed |