Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16408261 | 0.92 | SLC6A4 (0.41) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL16408198 | 0.92 | SLC6A4 (0.41) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL18780558 | 0.92 | SLC6A4 (0.41) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11283749 | 0.83 | KDM4E (0.51) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL1088743 | 0.83 | ALDH1A1 (0.40) | KDM4ECHRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL3006964 | 0.81 | KDM4E (0.38) | KDM4ECHRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL13744672 | 0.81 | KDM4E (0.39) | KDM4EMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL615680 | 0.77 | SLC6A4 (0.43) | CHRM1ALDH1A1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL13478888 | 0.77 | CHRM1 (0.42) | CHRM1ALDH1A1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL5901045 | 0.76 | SLC6A4 (0.43) | CHRM1SLC6A2SLC6A4KCNH2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022194-B1 | INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2017-05-17 | — | — | EP | disclosed |
| EP-3022193-B1 | INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-9573957-B2 | Inhibitors of leukotriene production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-21 | — | — | US | disclosed |
| US-9573957-B2 | Inhibitors of leukotriene production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-21 | — | — | US | disclosed |
| US-9303018-B2 | Inhibitors of leukotriene production | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-05 | — | — | US | disclosed |
| WO-2015009609-A1 | INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-22 | — | — | WO | disclosed |
| WO-2015009611-A1 | INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-01-22 | — | — | WO | disclosed |