Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642053 | 0.82 | MAPT (0.59) | KDM4EALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL1640326 | 0.80 | HSP90AA1 (0.58) | CNR2KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL1640573 | 0.78 | BRD4 (0.65) | ALDH1A1LMNARAB9AMAPTGAA | |
| SCHEMBL1642062 | 0.78 | NPC1 (0.51) | LMNANPC1RAB9AKMT2A | |
| SCHEMBL1642063 | 0.77 | KDR (0.56) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL1641834 | 0.77 | EGLN3 (0.71) | CNR2CNR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1640352 | 0.76 | LMNA (0.55) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL1641962 | 0.76 | NPC1 (0.54) | KDM4EALDH1A1ALOX15CHRNB2CHRNB4 | |
| SCHEMBL1641827 | 0.75 | BRD4 (0.57) | KMT2AMEN1MAPT | |
| SCHEMBL1641964 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1LMNAUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | CNR2 2738/4885CNR1 2636/4885KDM4E 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.