Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642053 | 0.89 | MAPT (0.59) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1642063 | 0.80 | KDR (0.56) | KDM4EALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL1641962 | 0.80 | NPC1 (0.54) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1642209 | 0.78 | EGLN1 (0.53) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL1640573 | 0.78 | BRD4 (0.65) | ALDH1A1HPGDHTTLMNASMN1; SMN2 | |
| SCHEMBL1640452 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1MEN1KMT2AKCNMA1 | |
| SCHEMBL1641073 | 0.77 | EGLN3 (0.67) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1640326 | 0.77 | HSP90AA1 (0.58) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1640352 | 0.76 | LMNA (0.55) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1641863 | 0.75 | TSHR (0.48) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
| EP-2306828-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxosmithkline LLC (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158315-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | KDM4E 521/4885ALDH1A1 227/4885MEN1 3669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.