Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.89 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.89 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.89 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.89 |
| ▸ | SRC | P12931 | 2/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.89 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.89 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.89 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.83 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.83 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.83 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.83 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.79 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.79 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.79 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.79 |
| ▸ | LDHA | P00338 | 1/20 | 0.79 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.79 |
| ▸ | FBP1 | P09467 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550321 | 1.00 | P2RY1 (0.89) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL13548849 | 1.00 | P2RY1 (0.89) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL21281726 | 1.00 | P2RY1 (0.89) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL15702880 | 1.00 | P2RY1 (0.89) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL16408122 | 1.00 | P2RY1 (0.89) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL26596813 | 1.00 | P2RY1 (0.89) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL15461708 | 0.99 | P2RY1 (0.91) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Diadenosine Tetraphosphate SCHEMBL4363130 | 0.94 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| Diadenosine Tetraphosphate SCHEMBL849869 | 0.94 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 | |
| SCHEMBL21067711 | 0.94 | P2RY1 (1.00) | P2RY1P2RY2P2RX1P2RX3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9452181-B2 | Composition for the management of nausea and vomiting | DUCHESNAY INC. (CA) | 2016-09-27 | — | — | US | disclosed |
| US-20150025032-A1 | Composition for the management of nausea and vomiting | DUCHESNAY INC. (CA) | 2015-01-22 | — | — | US | disclosed |
| US-20100016250-A1 | TOLL-LIKE RECEPTOR 9 AGONISTS | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016250-A1 | TOLL-LIKE RECEPTOR 9 AGONISTS | TLR9, TLR1, TLR7 | P2RY1 34/4885P2RY2 70/4885P2RX1 55/4885 |
| US-20150025032-A1 | Composition for the management of nausea and vomiting | CYP4F3, CYP2C19, SLC19A1 | P2RY1 653/4885P2RY2 888/4885P2RX1 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.