Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
| ▸ | CYCS | P99999 | 3/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556430 | 0.95 | TOP1 (0.50) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL249199 | 0.95 | TOP1 (0.50) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL31296593 | 0.95 | TOP1 (0.50) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL8865323 | 0.94 | TERT (0.51) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL29648445 | 0.94 | TERT (0.51) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL30297908 | 0.94 | TERT (0.51) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL14181439 | 0.91 | STAT3 (0.46) | TOP1STAT3STAT1CYCSENPP2 | |
| SCHEMBL14181438 | 0.91 | STAT3 (0.46) | TOP1STAT3STAT1CYCSENPP2 | |
| Phenol SCHEMBL28239621 | 0.91 | TOP1 (0.59) | TOP1STAT3STAT1CYCSENPP2 | |
| Temoporfin SCHEMBL6422 | 0.86 | TOP1 (0.43) | TOP1STAT3STAT1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098263-A1 | HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | CHE CHI MING | 2011-04-28 | — | — | US | claimed |
| CN-108779124-B | Gold porphyrin-PEG conjugates and methods of use | 香港大学 | 2022-03-01 | — | — | CN | disclosed |
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | THE UNIVERSITY OF HONG KONG (HK) | 2021-10-05 | — | — | US | disclosed |
| EP-3386986-B1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | UNIV HONG KONG (CN) | 2021-07-21 | — | — | EP | disclosed |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-08 | — | — | US | disclosed |
| US-8563712-B2 | Hydroxy-substituted gold(III) porphyrin complexes as histone deacetylase inhibitors | THE UNIVERSITY OF HONG KONG (HK) | 2013-10-22 | — | — | US | disclosed |
| EP-2493897-A1 | HYDROXY-SUBSTITUTED GOLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | The University of Hong Kong (CN) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011050575-A1 | HYDROXY-SUBSTITUTED GOLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF HONG KONG (CN) | 2011-05-05 | — | — | WO | disclosed |
| US-20110098263-A1 | HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | CHE CHI MING | 2011-04-28 | — | — | US | disclosed |
| US-6096557-A | USING A TETRAPHENYLPORPHYRIN OPTIONALLY COMPLEXED WITH ZINC TO DETECT HYDROGEN HALIDE GAS IN TEMPERATURE RANGE FROM 40 TO 80 DEGREES CELSIUS; WIDE MEASURABLE RANGE, QUICK RESPONSE AND WIDE LINEAR RELATIONSHIP | EBARA CORPORATION (JP) | 2000-08-01 | — | — | US | disclosed |
| EP-0824212-B1 | Gas detection method and apparatus using gas reactive pigment | EBARA CORP (JP) | 2000-03-22 | — | — | EP | disclosed |
| EP-0824212-A1 | Gas detection method and apparatus using gas reactive pigment | EBARA CORPORATION (JP) | 1998-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098263-A1 | HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC8, HDAC3 | TOP1 400/4885STAT3 600/4885STAT1 1798/4885 |
| US-11135310-B2 | Gold porphyrin-PEG conjugates and methods of use | HCCS, PPOX, LIG3 | TOP1 715/4885STAT3 2711/4885STAT1 3130/4885 |
| US-20170157261-A1 | GOLD PORPHYRIN-PEG CONJUGATES AND METHODS OF USE | HCCS, PPOX, LIG3 | TOP1 715/4885STAT3 2711/4885STAT1 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.