Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.47 |
| ▸ | CA2 | P00918 | 15/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947629 | 0.86 | CA1 (0.49) | CA1CA2MAOBCA12CA3 | |
| SCHEMBL17800814 | 0.83 | CA1 (0.47) | CA1CA2MAOBCA12CA3 | |
| SCHEMBL29469837 | 0.83 | CA1 (0.50) | CA1CA2CA12CA3CA4 | |
| SCHEMBL7143334 | 0.83 | CA1 (0.50) | CA1CA2CA12CA3CA4 | |
| SCHEMBL2393604 | 0.74 | CA1 (0.46) | CA1CA2CA12CA3CA4 | |
| SCHEMBL11375961 | 0.73 | BLM (0.50) | CA1CA2CA12CA3CA4 | |
| SCHEMBL22032277 | 0.73 | AHR (0.46) | — | |
| SCHEMBL16401424 | 0.72 | GAA (0.44) | CA1CA2MAOBCA12CA3 | |
| SCHEMBL11213161 | 0.72 | CA1 (0.44) | CA1CA2CA12CA3CA4 | |
| SCHEMBL13969592 | 0.72 | KDM4E (0.52) | CA1CA2MAOBCA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007668-A1 | HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2015-01-22 | — | — | WO | disclosed |