Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.44 |
| ▸ | CA2 | P00918 | 19/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375961 | 0.86 | BLM (0.50) | CA1CA2CA7CA13CA12 | |
| SCHEMBL7980708 | 0.81 | GSTO1 (0.49) | — | |
| SCHEMBL7980710 | 0.81 | GSTO1 (0.49) | — | |
| SCHEMBL11596834 | 0.81 | GSTO1 (0.49) | — | |
| SCHEMBL29469837 | 0.79 | CA1 (0.50) | CA1CA2CA7CA13CA12 | |
| SCHEMBL7143334 | 0.79 | CA1 (0.50) | CA1CA2CA7CA13CA12 | |
| SCHEMBL14870027 | 0.77 | CA2 (0.41) | CA1CA2CA7CA13CA12 | |
| SCHEMBL6926529 | 0.76 | HTR1A (0.45) | — | |
| SCHEMBL27529169 | 0.76 | HTR1A (0.45) | — | |
| SCHEMBL17800814 | 0.76 | CA1 (0.47) | CA1CA2CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023964-B1 | PHENYLIMINOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND INTERMEDIATES THEREFOR, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | disclosed |
| US-4346088-A | ANTILIPEMICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-24 | — | — | US | disclosed |
| EP-0023964-A1 | Phenyliminothiazoline derivatives, their preparation and intermediates therefor, pharmaceutical preparations containing them and their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-02-18 | — | — | EP | disclosed |