SCHEMBL16401424

SCHEMBL16401424

CC(c1ccc(Cl)c(S(N)(=O)=O)c1)n1cccn1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.44
CA1 P00915 15/20 0.39
CA2 P00918 15/20 0.39
CA7 P43166 7/20 0.39
CA13 Q8N1Q1 7/20 0.39
CA12 O43570 6/20 0.39
CA9 Q16790 6/20 0.39
CA6 P23280 5/20 0.39
CA3 P07451 4/20 0.39
CA4 P22748 4/20 0.39
CA5A P35218 4/20 0.39
CA14 Q9ULX7 4/20 0.39
CA5B Q9Y2D0 4/20 0.39
MAOB P27338 1/20 0.38
MMP2 P08253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13947629 0.75 CA1 (0.49) GAACA1CA2CA7CA13
SCHEMBL7143334 0.72 CA1 (0.50) CA1CA2CA7CA13CA12
SCHEMBL16410189 0.72 CA1 (0.47) CA1CA2CA7CA13CA12
SCHEMBL29469837 0.72 CA1 (0.50) CA1CA2CA7CA13CA12
SCHEMBL17800814 0.72 CA1 (0.47) CA1CA2CA7CA13CA12
SCHEMBL22369257 0.68 CYP2D6 (0.45)
SCHEMBL15174490 0.68 CYP2D6 (0.45)
SCHEMBL16401427 0.68 CA1 (0.49) GAACA1CA2CA7CA13
SCHEMBL24961335 0.67 HRH1 (0.42) GAA
SCHEMBL29026700 0.67 HRH1 (0.39) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160159805-A1 Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-09 US disclosed
US-20160159805-A1 Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-09 US disclosed
US-20160159805-A1 Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-09 US disclosed
EP-3021673-A1 HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES Bayer CropScience Aktiengesellschaft (DE) 2016-05-25 EP disclosed
WO-2015007668-A1 HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2015-01-22 WO disclosed
WO-2015007668-A1 HETEROCYCLIC SULFONYLAMINO(THIO)CARBONYL-DERIVATIVES WITH NEMATICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2015-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159805-A1 Heterocyclic sulfonylamino(thio)carbonyl-derivatives with nematicidal properties TST, TUBB, TUBA3C GAA 2256/4885CA1 3866/4885CA2 2143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.