Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 12/20 | 0.51 |
| ▸ | F11 | P03951 | 10/20 | 0.51 |
| ▸ | TPSB2 | P20231 | 9/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410528 | 0.89 | MRGPRX4 (0.41) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16396196 | 0.89 | BRD4 (0.40) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16397186 | 0.89 | BRD4 (0.40) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL17764225 | 0.89 | CCR5 (0.44) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16397752 | 0.89 | BRD4 (0.40) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16410362 | 0.88 | CFD (0.42) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16396606 | 0.88 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL17764385 | 0.87 | ACACB (0.39) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16397233 | 0.87 | HDAC1 (0.41) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL16410458 | 0.87 | CFD (0.44) | CFDF11TPSB2KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009977-A1 | AMINOMETHYL-BIARYL DERIVATIVES AS COMPLEMENT FACTOR D INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2015-01-22 | — | — | WO | disclosed |