Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506373 | 0.80 | CSNK2A1 (0.66) | CSNK2A1MRGPRX4GLASMN1; SMN2TAAR1 | |
| SCHEMBL28467993 | 0.79 | CSNK2A1 (0.60) | CSNK2A1MRGPRX4ROCK2ROCK1GLA | |
| SCHEMBL3118077 | 0.79 | CSNK2A1 (0.56) | CSNK2A1MRGPRX4ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL856874 | 0.78 | CSNK2A1 (0.67) | CSNK2A1MRGPRX4GLASMN1; SMN2TAAR1 | |
| SCHEMBL506790 | 0.77 | CSNK2A1 (0.75) | CSNK2A1MRGPRX4GLASMN1; SMN2CSNK2A2 | |
| SCHEMBL4550411 | 0.77 | CSNK2A1 (0.59) | CSNK2A1MRGPRX4ROCK2ROCK1GLA | |
| Hydrochloric Acid SCHEMBL3110229 | 0.76 | CSNK2A1 (0.76) | CSNK2A1MRGPRX4GLASMN1; SMN2CSNK2A2 | |
| SCHEMBL6215544 | 0.76 | CSNK2A1 (1.00) | CSNK2A1MRGPRX4ROCK2ROCK1GLA | |
| Hydrochloric Acid SCHEMBL2716247 | 0.75 | CSNK2A1 (0.60) | CSNK2A1MRGPRX4GLASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15350295 | 0.75 | CSNK2A1 (0.60) | CSNK2A1MRGPRX4GLASMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015009930-A2 | NOVEL PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-01-22 | — | — | WO | disclosed |