Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506373 | 0.87 | CSNK2A1 (0.66) | CSNK2A1MEN1ALDH1A1KMT2AMRGPRX4 | |
| Hydrochloric Acid SCHEMBL856874 | 0.85 | CSNK2A1 (0.67) | CSNK2A1MEN1ALDH1A1KMT2AMRGPRX4 | |
| SCHEMBL16411005 | 0.79 | CSNK2A1 (0.61) | CSNK2A1MRGPRX4SMN1; SMN2GLACSNK2A2 | |
| SCHEMBL16216977 | 0.76 | CSNK2A1 (0.53) | CSNK2A1MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL506790 | 0.76 | CSNK2A1 (0.75) | CSNK2A1MRGPRX4SMN1; SMN2GLACSNK2A2 | |
| Hydrochloric Acid SCHEMBL3110229 | 0.75 | CSNK2A1 (0.76) | CSNK2A1MRGPRX4SMN1; SMN2GLACSNK2A2 | |
| SCHEMBL6215544 | 0.75 | CSNK2A1 (1.00) | CSNK2A1MEN1KMT2AMRGPRX4SMN1; SMN2 | |
| SCHEMBL8349185 | 0.74 | KDM4E (0.56) | CSNK2A1MEN1ALDH1A1KMT2A | |
| SCHEMBL714973 | 0.73 | KDM4E (0.70) | MEN1ALDH1A1KMT2ASMN1; SMN2GLA | |
| SCHEMBL28193125 | 0.72 | CSNK2A1 (0.57) | CSNK2A1ALDH1A1MRGPRX4CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553607-B | Pyrimidine carboxamide derivatives, preparation method, composition, preparation and application thereof | 镇江圣安医药有限公司 | 2020-09-01 | — | — | CN | disclosed |