Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.73 |
| ▸ | CTSB | P07858 | 17/20 | 0.73 |
| ▸ | CTSF | Q9UBX1 | 17/20 | 0.73 |
| ▸ | CTSK | P43235 | 5/20 | 0.58 |
| ▸ | CTSS | P25774 | 4/20 | 0.58 |
| ▸ | CTSV | O60911 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL16412066 | 0.88 | CTSL (0.74) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL12999171 | 0.86 | CTSL (0.80) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL2927165 | 0.85 | CTSB (0.79) | CTSLCTSBCTSFCTSKCTSS | |
| Bicarbonate SCHEMBL16411969 | 0.85 | CTSL (0.75) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL12999161 | 0.85 | CTSL (0.79) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL12999166 | 0.85 | CTSL (0.79) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL12999181 | 0.84 | CTSL (0.78) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL3765380 | 0.84 | CTSB (1.00) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL3759357 | 0.84 | CTSB (1.00) | CTSLCTSBCTSFCTSKCTSS | |
| SCHEMBL2953108 | 0.84 | CTSB (1.00) | CTSLCTSBCTSFCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225196-B1 | CYSTEINE PROTEASE INHIBITORS FOR THE TREATMENT OF PARASITIC DISEASES | MERCK CANADA INC (CA) | 2015-01-28 | — | — | EP | claimed |