SCHEMBL16418239

SCHEMBL16418239

FC(C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3056072 1.00 LMNA (0.38) LMNATHRB
SCHEMBL14762028 0.97 LMNA (0.33) LMNA
SCHEMBL8672889 0.91 LMNA (0.36) LMNATHRB
SCHEMBL29743191 0.90 LMNA (0.30) LMNA
SCHEMBL1687045 0.88 LMNA (0.32) LMNA
SCHEMBL7773758 0.85 LMNA (0.36) LMNATHRB
SCHEMBL3629754 0.85 LMNA (0.36) LMNATHRB
SCHEMBL1526904 0.85 LMNA (0.36) LMNATHRB
SCHEMBL3626391 0.85 LMNA (0.36) LMNATHRB
SCHEMBL5165029 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8946364-B2 Solution phase polydiacetylene synthesis by alkyne metathesis EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-02-03 US claimed